Mental Health

Mental health problems are set to become one of the world’s biggest causes of ill health by 2030, already affecting millions globally each year and causing significant social and economic impacts.

While some treatments work for some people, some of the time, we urgently need to find better approaches that can help more people globally. Wellcome is helping to define a new era of mental health science that will speed progress by combining strengths from many areas of research.

We’re funding cutting-edge science to understand how brain, body and environment interact in mental health problems, to unpick how successful interventions work, and to develop treatments and approaches that are more effective and more personalised.

Over the next 30 years, we will help find the next generations of treatments and approaches to help prevent or treat mental ill health. Right now, we are:

• supporting the mental health science community to agree common ways to measure mental health outcomes, so that researchers can compare and consider results across different studies and disciplines
• encouraging and enabling connections across the research community
• involving people with lived experience every step of the way so that the ways we address mental health challenges are meaningful to those most affected.

Wellcome also funds discovery research in a broad range of disciplines, including mental health. Insights and tools from this research will contribute to solving this health challenge, as well as increasing broader understanding of life, health and wellbeing.

Read more about what we want to achieve in the mental health space in the next 30 years.

We want the broadest range of people to contribute to and benefit from equitable solutions to mental health problems. That’s why we work with researchers, people with lived experience, policy makers, activists, community leaders and businesses in all parts of the world.

We’re currently working on: 

To help deliver our vision across three key health challenges, we support research through a combination of open calls and direct funding approaches.  

We work with and fund a diverse group of people who can bring innovative and creative insights to these urgent health challenges. 

We often have calls for specific research projects as part of our mental health work, open to applicants and teams in any country. Our funding covers both back-translation (working backwards from the evidence of what works to understand why) and forward-translation (developing new approaches from theories developed out of basic discovery research). 

This page will be updated regularly with the latest mental health funding information and the opportunities we have available for discovery research.

• Dr Kate Martin, Lived Experience and Public Engagement Lead, Wellcome
• Dr Cat Sebastian, Evidence Lead, Wellcome