What we do and don’t fund in discovery research

This includes research into the:   

• fundamental processes that underpin biology, to understand more about how life works  
• complexities of human health and disease, including clinical and population-based approaches 
• development of methodologies, conceptual frameworks, technologies, tools or techniques that could benefit health-related research  
• needs, values and priorities of the people and communities affected by disease and health disparities 
• social, cultural, political and historical contexts of human health and disease. 

Research can involve experimental or theoretical approaches. It can be carried out in the laboratory, office, clinic or field.  

Inclusivity is at the heart of our approach and we fund people at all career stages, from a broad range of disciplines. 

This includes, but is not limited to: 

• science, technology, engineering and maths (STEM) 
• humanities and social science 
• clinical/allied health sciences 
• experimental medicine 
• public health. 

We fund individuals and teams of researchers. 

Our schemes are open to applicants based in the UK, the Republic of Ireland and low- and middle-income countries, and coapplicants from the rest of the world if applying as part of a team.  

We particularly welcome applications that bring together different disciplines to tackle problems creatively and with new perspectives. 

Under our discovery research remit, we don’t support: 

• research aimed at developing or implementing interventions or therapeutics - however we are interested in fundamental research that could lead to such intervention development  
• investigations involving humans as participants to demonstrate evidence of the validity and importance of new treatments 
• proof-of-principle experiments that lay the groundwork for further clinical trials 
• studies on companion and exotic animals, except as models for human disease. 

Research doesn’t have to be related to our three health challenge programmes: mental health, climate, and infectious disease. Each programme will fund research and other activities according to its goals and defined set of outcomes. This may be through directed funding or through one-off open calls from time to time. We'll provide more information as our strategy for each programme develops.   

Most of our previous funding schemes will close during 2021.  

For science and humanities and social science schemes, our previous remits will still apply. Check the relevant scheme page for details.